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Glioblastoma multiforme
Glioblastoma multiforme Classification and external resources ICD-10 C71 ICD-9 191 ICD-O: M9440/3 OMIM 137800 DiseasesDB 29448 eMedicine neuro/147 med/2692 MeSH D005909 Glioblastoma multiforme (GBM), WHO classification name "glioblastoma", is the most common and most aggressive malignant primary brain tumor in humans, involving glial cells and accounting for 52% of all functional tissue brain tumor cases and 20% of all intracranial tumors. GBM is rare, with incidence of 2–3 cases per 100,000 in Europe and North America. It presents two variants: giant cell glioblastoma and gliosarcoma.Treatment can involve chemotherapy, radiation and surgery. Median survival with standard-of-care radiation and chemotherapy with temozolomide is 15 months. Median survival without treatment is 4½ months. Although no randomized controlled trials have been done, surgery remains the standard of care. Cite error: There are tags on this page, but the references will not show without a {{reflist}} template (see the help page).
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